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ReHap: A Framework for Single Individual Haplotyping from Next-Generation Sequencing Data

Next-Generation Sequencing technologies (NGS) are trasforming today’s biology by making it economically feasible to read the complete genome of individuals. Single nucleotide polymorphism (SNP) is the most common form of individual DNA variation; and the set of SNPs present in a chromosome (called the haplotype) is of interest in a wide area of applications in molecular biology and biomedicine. Personalized haplotyping of (portions of/all) the chromosomes of individuals through NGS is one of themost promising basic ingredients leading


2011

Autori IIT:

Tipo: Capitoli di libro con casa editrice internazionale
Area di disciplina: Computer Science & Engineering

Attività: Biologia computazionale